LBX1

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Ladybird homeobox 1
Identifiers
Symbols LBX1 ; HPX-6; HPX6; LBX1H; homeobox
External IDs OMIM604255 MGI104867 HomoloGene4784 GeneCards: LBX1 Gene
RNA expression pattern
PBB GE LBX1 208380 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10660 16814
Ensembl ENSG00000138136 ENSMUSG00000025216
UniProt P52954 P52955
RefSeq (mRNA) NM_006562 NM_010691
RefSeq (protein) NP_006553 NP_034821
Location (UCSC) Chr 10:
102.99 – 102.99 Mb
Chr 19:
45.23 – 45.24 Mb
PubMed search [1] [2]

Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene.[1][2]

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.[2]

References[edit]

  1. ^ Jagla K, Dolle P, Mattei MG, Jagla T, Schuhbaur B, Dretzen G, Bellard F, Bellard M (Jul 1996). "Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes". Mech Dev 53 (3): 345–56. doi:10.1016/0925-4773(95)00450-5. PMID 8645601. 
  2. ^ a b "Entrez Gene: LBX1 ladybird homeobox 1". 

Further reading[edit]