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Ladybird homeobox 1
Symbols LBX1 ; HPX-6; HPX6; LBX1H; homeobox
External IDs OMIM604255 MGI104867 HomoloGene4784 GeneCards: LBX1 Gene
RNA expression pattern
PBB GE LBX1 208380 at tn.png
More reference expression data
Species Human Mouse
Entrez 10660 16814
Ensembl ENSG00000138136 ENSMUSG00000025216
UniProt P52954 P52955
RefSeq (mRNA) NM_006562 NM_010691
RefSeq (protein) NP_006553 NP_034821
Location (UCSC) Chr 10:
102.99 – 102.99 Mb
Chr 19:
45.23 – 45.24 Mb
PubMed search [1] [2]

Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene.[1][2]

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.[2]


  1. ^ Jagla K, Dolle P, Mattei MG, Jagla T, Schuhbaur B, Dretzen G, Bellard F, Bellard M (Jul 1996). "Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes". Mech Dev 53 (3): 345–56. doi:10.1016/0925-4773(95)00450-5. PMID 8645601. 
  2. ^ a b "Entrez Gene: LBX1 ladybird homeobox 1". 

Further reading[edit]