FOXN3

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Forkhead box N3
Identifiers
Symbols FOXN3 ; C14orf116; CHES1; PRO1635
External IDs OMIM602628 MGI1918625 HomoloGene3809 GeneCards: FOXN3 Gene
RNA expression pattern
PBB GE CHES1 205022 s at tn.png
PBB GE CHES1 205021 s at tn.png
PBB GE CHES1 218031 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1112 71375
Ensembl ENSG00000053254 ENSMUSG00000033713
UniProt O00409 Q499D0
RefSeq (mRNA) NM_001085471 NM_183186
RefSeq (protein) NP_001078940 NP_899009
Location (UCSC) Chr 14:
89.59 – 90.09 Mb
Chr 12:
99.19 – 99.45 Mb
PubMed search [1] [2]

Forkhead box protein N3 is a protein that in humans is encoded by the FOXN3 gene.[1][2]

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.[2]

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