Eomesodermin

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Eomesodermin
Identifiers
Symbols EOMES ; TBR2
External IDs OMIM604615 HomoloGene3971 GeneCards: EOMES Gene
Orthologs
Species Human Mouse
Entrez 8320 13813
Ensembl ENSG00000163508 ENSMUSG00000032446
UniProt O95936 O54839
RefSeq (mRNA) NM_005442 NM_001164789
RefSeq (protein) NP_005433 NP_001158261
Location (UCSC) Chr 3:
27.76 – 27.76 Mb
Chr 9:
118.48 – 118.49 Mb
PubMed search [1] [2]

Eomesodermin also known as T-box brain protein 2 (TBR2) is a protein that in humans is encoded by the EOMES gene.[1]

This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.[1]

See also[edit]

References[edit]

  1. ^ a b "Entrez Gene: Eomesodermin". Retrieved 2011-11-01. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.