Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14gene. The corresponding Klf14 mouse gene is known as Sp6.
Like the other members of the KLF family, KLF14 has three zinc-finger domains near the C-terminus, all three of which are of the classical C2H2 type. In the human, they are at amino acids 195–219, 225–249, and 255–277.
Human KLF14 is 323 amino acids in length, with a molecular weight of 33,124; in the mouse its length is 325.
^the MuTHER, Consortium; Small, KS, Hedman, AK, Grundberg, E, Nica, AC, Thorleifsson, G, Kong, A, Thorsteindottir, U, Shin, SY, Richards, HB, the GIANT, Consortium, the MAGIC, Investigators, the DIAGRAM, Consortium, Soranzo, N, Ahmadi, KR, Lindgren, CM, Stefansson, K, Dermitzakis, ET, Deloukas, P, Spector, TD, McCarthy, MI (May 15, 2011). "Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.". Nature Genetics43 (6). doi:10.1038/ng.833. PMID21572415.Cite uses deprecated parameters (help)