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General transcription factor IIH, polypeptide 4, 52kDa
Symbols GTF2H4 ; P52; TFB2; TFIIH
External IDs OMIM601760 MGI1338799 HomoloGene7090 GeneCards: GTF2H4 Gene
RNA expression pattern
PBB GE GTF2H4 203577 at tn.png
More reference expression data
Species Human Mouse
Entrez 2968 14885
Ensembl ENSG00000213780 ENSMUSG00000001524
UniProt Q92759 O70422
RefSeq (mRNA) NM_001517 NM_010364
RefSeq (protein) NP_001508 NP_034494
Location (UCSC) Chr 6:
30.88 – 30.88 Mb
Chr 17:
35.67 – 35.67 Mb
PubMed search [1] [2]

General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.[1][2]


GTF2H4 has been shown to interact with:

See also[edit]


  1. ^ a b Marinoni JC, Roy R, Vermeulen W, Miniou P, Lutz Y, Weeda G et al. (Apr 1997). "Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH". EMBO J. 16 (5): 1093–102. doi:10.1093/emboj/16.5.1093. PMC 1169708. PMID 9118947. 
  2. ^ "Entrez Gene: GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa". 
  3. ^ a b c d e Scully R, Anderson SF, Chao DM, Wei W, Ye L, Young RA et al. (May 1997). "BRCA1 is a component of the RNA polymerase II holoenzyme". Proc. Natl. Acad. Sci. U.S.A. 94 (11): 5605–10. doi:10.1073/pnas.94.11.5605. PMC 20825. PMID 9159119. 
  4. ^ Giglia-Mari G, Coin F, Ranish JA, Hoogstraten D, Theil A, Wijgers N et al. (Jul 2004). "A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A". Nat. Genet. 36 (7): 714–9. doi:10.1038/ng1387. PMID 15220921. 

Further reading[edit]

External links[edit]