Activating protein 2

transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Identifiers
Symbol	TFAP2B
Alt. symbols	AP2-B
NCBI gene	7021
HGNC	11743
OMIM	601601
RefSeq	NM_003221
UniProt	Q92481
Other data
Locus	Chr. 6 p12
Structures
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Structures	Swiss-model
Domains	InterPro

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Structures	Swiss-model
Domains	InterPro

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Identifiers
Symbol	TFAP2A
Alt. symbols	TFAP2, AP2TF
NCBI gene	7020
HGNC	11742
OMIM	107580
RefSeq	NM_003220
UniProt	P05549
Other data
Locus	Chr. 6 p22.3
Structures
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Structures	Swiss-model
Domains	InterPro

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Identifiers

Symbol

TFAP2C

Other data

Chr. 20 q13.2

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Structures	Swiss-model
Domains	InterPro

transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

Identifiers

Symbol

TFAP2D

Alt. symbols

TFAP2BL1

Other data

Chr. 6 p12.3

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Structures	Swiss-model
Domains	InterPro

transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)

Identifiers

Symbol

TFAP2E

Alt. symbols

AP2E

Other data

Chr. 1 p34.3

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Structures	Swiss-model
Domains	InterPro

Activating Protein 2 (AP-2) is a family of closely related transcription factors^[1]^[2] which plays a critical role in regulating gene expression during early development.^[3]

References

^ Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science. 251 (4997): 1067–71. Bibcode:1991Sci...251.1067W. doi:10.1126/science.1998122. PMID 1998122.
^ Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi:10.1101/gad.5.4.670. PMID 2010091.
^ Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene. 260 (1–2): 1–12. doi:10.1016/S0378-1119(00)00454-6. PMID 11137286.

External links

Transcription+Factor+AP-2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[pmid1998122-1] Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science. 251 (4997): 1067–71. Bibcode:1991Sci...251.1067W. doi:10.1126/science.1998122. PMID 1998122.

[pmid2010091-2] Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi:10.1101/gad.5.4.670. PMID 2010091.

[pmid11137286-3] Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene. 260 (1–2): 1–12. doi:10.1016/S0378-1119(00)00454-6. PMID 11137286.

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[2]

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