CCAAT/enhancer-binding protein gamma is a protein that in humans is encoded by the CEBPGgene.
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements.
^Williams SC, Cantwell CA, Johnson PF (Oct 1991). "A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro". Genes Dev. 5 (9): 1553–67. doi:10.1101/gad.5.9.1553. PMID1884998.
Nishizawa M, Nagata S (1992). "cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein.". FEBS Lett. 299 (1): 36–8. doi:10.1016/0014-5793(92)80094-W. PMID1371974.
Nishizawa M, Wakabayashi-Ito N, Nagata S (1991). "Molecular cloning of cDNA and a chromosomal gene encoding GPE1-BP, a nuclear protein which binds to granulocyte colony-stimulating factor promoter element 1.". FEBS Lett. 282 (1): 95–7. doi:10.1016/0014-5793(91)80452-9. PMID1709121.
Davydov IV, Bohmann D, Krammer PH, Li-Weber M (1995). "Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter.". Gene. 161 (2): 271–5. doi:10.1016/0378-1119(95)00271-7. PMID7665092.
Lundgren M, Larsson C, Femino A, et al. (1994). "Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site.". J. Immunol. 153 (7): 2983–95. PMID8089482.
Hattori T, Ohoka N, Inoue Y, et al. (2003). "C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.". Oncogene. 22 (9): 1273–80. doi:10.1038/sj.onc.1206204. PMID12618752.