Transcriptional enhancer factor TEF-3 is a protein that in humans is encoded by the TEAD4gene.
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
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Jacquemin P, Hwang JJ, Martial JA, et al. (1996). "A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain". J. Biol. Chem.271 (36): 21775–85. doi:10.1074/jbc.271.36.21775. PMID8702974.
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Vaudin P, Delanoue R, Davidson I, et al. (1999). "TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation". Development126 (21): 4807–16. PMID10518497.