Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene. [1 ] [2 ]
Function [ edit ]
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.
See also [ edit ]
References [ edit ]
Further reading [ edit ]
Huebner K, Druck T, Croce CM, Thiesen HJ (Apr 1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". American Journal of Human Genetics 48 (4): 726–40. PMC 1682948. PMID 2014798.
Bellefroid EJ, Poncelet DA, Lecocq PJ, Revelant O, Martial JA (May 1991). "The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins". Proceedings of the National Academy of Sciences of the United States of America 88 (9): 3608–12. doi: 10.1073/pnas.88.9.3608. PMC 51501. PMID 2023909.
Thiesen HJ (Apr 1990). "Multiple genes encoding zinc finger domains are expressed in human T cells". The New Biologist 2 (4): 363–74. PMID 2288909.
Bellefroid EJ, Marine JC, Ried T, Lecocq PJ, Rivière M, Amemiya C et al. (Apr 1993). "Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells". The EMBO Journal 12 (4): 1363–74. PMC 413348. PMID 8467795.
Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research 10 (11): 1788–95. doi: 10.1101/gr.143000. PMC 310948. PMID 11076863.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports 1 (3): 287–92. doi: 10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A et al. (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research 14 (10B): 2136–44. doi: 10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F et al. (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research 34 (Database issue): D415–8. doi: 10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Takahashi T, Furuchi T, Naganuma A (Dec 2006). "Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells". Cancer Research 66 (24): 11932–7. doi: 10.1158/0008-5472.CAN-06-3220. PMID 17178891.
External links [ edit ]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.