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Zinc finger protein 300
Symbols ZNF300 ; DKFZp686B24204
External IDs OMIM612429 MGI3045326 HomoloGene56531 GeneCards: ZNF300 Gene
Species Human Mouse
Entrez 91975 245368
Ensembl ENSG00000145908 ENSMUSG00000031079
UniProt Q96RE9 A2AE21
RefSeq (mRNA) NM_001172831 NM_183185.3
RefSeq (protein) NP_001166302 NP_899008.2
Location (UCSC) Chr 5:
150.89 – 150.9 Mb
Chr X:
20.66 – 20.67 Mb
PubMed search [1] [2]

Zinc finger protein 300 is a protein that in humans is encoded by the ZNF300 gene.[1][2] The protein encoded by this gene is a C2H2-type zinc finger DNA binding protein and a likely transcription factor.

Clinical relevance[edit]

It is associated with Crohn's disease.[3]


  1. ^ Gou D, Wang J, Gao L, Sun Y, Peng X, Huang J, Li W (January 2004). "Identification and functional analysis of a novel human KRAB/C2H2 zinc finger gene ZNF300". Biochim. Biophys. Acta 1676 (2): 203–9. doi:10.1016/j.bbaexp.2003.11.011. PMID 14746915. 
  2. ^ "Entrez Gene: zinc finger protein 300". 
  3. ^ Prescott NJ, Dominy KM, Kubo M, Lewis CM, Fisher SA, Redon R, Huang N, Stranger BE, Blaszczyk K, Hudspith B, Parkes G, Hosono N, Yamazaki K, Onnie CM, Forbes A, Dermitzakis ET, Nakamura Y, Mansfield JC, Sanderson J, Hurles ME, Roberts RG, Mathew CG (May 2010). "Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease". Hum. Mol. Genet. 19 (9): 1828–39. doi:10.1093/hmg/ddq041. PMC 2850616. PMID 20106866. 

Further reading[edit]