ARID3A

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ARID3A
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ARID3A, BRIGHT, DRIL1, DRIL3, E2FBP1, AT-rich interaction domain 3A
External IDs MGI: 1328360 HomoloGene: 124247 GeneCards: 1820
RNA expression pattern
PBB GE ARID3A 205865 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005224

NM_001288625
NM_001288626
NM_007880

RefSeq (protein)

NP_005215.1

NP_001275554.1
NP_001275555.1
NP_031906.1

Location (UCSC) Chr 19: 0.93 – 0.98 Mb Chr 10: 79.93 – 79.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene.[1][2]

Function[edit]

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.[2]

Interactions[edit]

ARID3A has been shown to interact with:

References[edit]

  1. ^ Kortschak RD, Reimann H, Zimmer M, Eyre HJ, Saint R, Jenne DE (Jul 1998). "The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome". Genomics 51 (2): 288–92. doi:10.1006/geno.1998.5259. PMID 9722953. 
  2. ^ a b "Entrez Gene: ARID3A AT rich interactive domain 3A (BRIGHT-like)". 
  3. ^ Nixon JC, Rajaiya JB, Ayers N, Evetts S, Webb CF (Mar 2004). "The transcription factor, Bright, is not expressed in all human B lymphocyte subpopulations". Cellular Immunology 228 (1): 42–53. doi:10.1016/j.cellimm.2004.03.004. PMID 15203319. 
  4. ^ Suzuki M, Okuyama S, Okamoto S, Shirasuna K, Nakajima T, Hachiya T, Nojima H, Sekiya S, Oda K (Aug 1998). "A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer". Oncogene 17 (7): 853–65. doi:10.1038/sj.onc.1202163. PMID 9780002. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.