HIVEP1

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HIVEP1
Protein HIVEP1 PDB 1bbo.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HIVEP1, CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A, human immunodeficiency virus type I enhancer binding protein 1
External IDs MGI: 96100 HomoloGene: 1596 GeneCards: 3096
Genetically Related Diseases
Disease Name References
substance dependence
RNA expression pattern
PBB GE HIVEP1 204512 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002114

NM_007772

RefSeq (protein)

NP_002105.3

n/a

Location (UCSC) Chr 6: 12.01 – 12.16 Mb Chr 13: 42.05 – 42.19 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 40 is a protein that in humans is encoded by the HIVEP1 gene.[4][5]

Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM][5]

References[edit]

  1. ^ "chibi.ubc.ca/Gemma/phenotypes.html?phenotypeUrlId=DOID_9973&geneId=61425". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Gaynor RB, Muchardt C, Diep A, Mohandas TK, Sparkes RS, Lusis AJ (Jul 1991). "Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24". Genomics. 9 (4): 758–61. doi:10.1016/0888-7543(91)90371-K. PMID 2037300. 
  5. ^ a b "Entrez Gene: HIVEP1 human immunodeficiency virus type I enhancer binding protein 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.