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Zinc finger protein 365
Symbols ZNF365 ; Su48; UAN; ZNF365D
External IDs OMIM607818 MGI2143676 HomoloGene8975 GeneCards: ZNF365 Gene
RNA expression pattern
PBB GE ZNF365 206448 at tn.png
More reference expression data
Species Human Mouse
Entrez 22891 216049
Ensembl ENSG00000138311 ENSMUSG00000037855
UniProt Q70YC4 Q8BG89
RefSeq (mRNA) NM_014951 NM_178679
RefSeq (protein) NP_055766 NP_848794
Location (UCSC) Chr 10:
62.37 – 62.67 Mb
Chr 10:
67.89 – 67.91 Mb
PubMed search [1] [2]

Protein ZNF365 is a protein that in humans is encoded by the ZNF365 gene.[1][2][3]

Model organisms[edit]

Model organisms have been used in the study of ZNF365 function. A conditional knockout mouse line called Zfp365tm1a(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute.[4] Male and female animals underwent a standardized phenotypic screen[5] to determine the effects of deletion.[6][7][8][9] Additional screens performed: - In-depth immunological phenotyping[10] - in-depth bone and cartilage phenotyping[11]


  1. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485. 
  2. ^ Gianfrancesco F, Esposito T, Ombra MN, Forabosco P, Maninchedda G, Fattorini M, Casula S, Vaccargiu S, Casu G, Cardia F, Deiana I, Melis P, Falchi M, Pirastu M (May 2003). "Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate". Am J Hum Genet 72 (6): 1479–91. doi:10.1086/375628. PMC 1180308. PMID 12740763. 
  3. ^ "Entrez Gene: ZNF365 zinc finger protein 365". 
  4. ^ Gerdin AK (2010). "The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice". Acta Opthalmologica 88: 925-7.doi:10.1111/j.1755-3768.2010.4142.x: Wiley. 
  5. ^ a b "International Mouse Phenotyping Consortium". 
  6. ^ Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (Jun 2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature 474 (7351): 337–42. doi:10.1038/nature10163. PMC 3572410. PMID 21677750. 
  7. ^ Dolgin E (Jun 2011). "Mouse library set to be knockout". Nature 474 (7351): 262–3. doi:10.1038/474262a. PMID 21677718. 
  8. ^ Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell 128 (1): 9–13. doi:10.1016/j.cell.2006.12.018. PMID 17218247. 
  9. ^ White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, Sanger Institute Mouse Genetics Project, Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP (2013). "Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes". Cell 154 (2): 452–64. doi:10.1016/j.cell.2013.06.022. PMID 23870131. 
  10. ^ a b "Infection and Immunity Immunophenotyping (3i) Consortium". 
  11. ^ a b "OBCD Consortium". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.