ZNF365

From Wikipedia, the free encyclopedia
Jump to: navigation, search
ZNF365
Identifiers
Aliases ZNF365, Su48, UAN, ZNF365D, zinc finger protein 365
External IDs MGI: 2143676 HomoloGene: 8975 GeneCards: 22891
Genetically Related Diseases
Disease Name References
narcolepsy
breast cancer
atopic dermatitis
RNA expression pattern
PBB GE ZNF365 206448 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014951
NM_199450
NM_199451
NM_199452

NM_178679

RefSeq (protein)

NP_955524.3
NP_055766.2
NP_955522.1
NP_955523.1

NP_848794.1

Location (UCSC) Chr 10: 62.37 – 62.67 Mb Chr 10: 67.89 – 67.91 Mb
PubMed search [4] [5]
Wikidata
View/Edit Human View/Edit Mouse

Protein ZNF365 is a protein that in humans is encoded by the ZNF365 gene.[6][7][8]

Model organisms[edit]

Model organisms have been used in the study of ZNF365 function. A conditional knockout mouse line called Zfp365tm1a(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute.[9] Male and female animals underwent a standardized phenotypic screen[10] to determine the effects of deletion.[11][12][13][14] Additional screens performed: - In-depth immunological phenotyping[15] - in-depth bone and cartilage phenotyping[16]

References[edit]

  1. ^ "chibi.ubc.ca/Gemma/phenotypes.html?phenotypeUrlId=DOID_8986&geneId=233162". 
  2. ^ "chibi.ubc.ca/Gemma/phenotypes.html?phenotypeUrlId=DOID_1612&geneId=233162". 
  3. ^ "chibi.ubc.ca/Gemma/phenotypes.html?phenotypeUrlId=DOID_3310&geneId=233162". 
  4. ^ "Human PubMed Reference:". 
  5. ^ "Mouse PubMed Reference:". 
  6. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485. 
  7. ^ Gianfrancesco F, Esposito T, Ombra MN, Forabosco P, Maninchedda G, Fattorini M, Casula S, Vaccargiu S, Casu G, Cardia F, Deiana I, Melis P, Falchi M, Pirastu M (Jun 2003). "Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate". American Journal of Human Genetics. 72 (6): 1479–91. doi:10.1086/375628. PMC 1180308free to read. PMID 12740763. 
  8. ^ "Entrez Gene: ZNF365 zinc finger protein 365". 
  9. ^ Gerdin AK (2010). "The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice". Acta Ophthalmologica. 88: 925–7. doi:10.1111/j.1755-3768.2010.4142.x. 
  10. ^ a b "International Mouse Phenotyping Consortium". 
  11. ^ Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (Jun 2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–42. doi:10.1038/nature10163. PMC 3572410free to read. PMID 21677750. 
  12. ^ Dolgin E (Jun 2011). "Mouse library set to be knockout". Nature. 474 (7351): 262–3. doi:10.1038/474262a. PMID 21677718. 
  13. ^ Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9–13. doi:10.1016/j.cell.2006.12.018. PMID 17218247. 
  14. ^ White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP (Jul 2013). "Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes". Cell. 154 (2): 452–64. doi:10.1016/j.cell.2013.06.022. PMC 3717207free to read. PMID 23870131. 
  15. ^ a b "Infection and Immunity Immunophenotyping (3i) Consortium". 
  16. ^ a b "OBCD Consortium". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.