Hepatocyte nuclear factor 4 gamma

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  (Redirected from HNF4G (gene))
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Protein HNF4G PDB 1lv2.png
Available structures
PDBOrtholog search: PDBe RCSB
AliasesHNF4G, NR2A2, NR2A3, Hepatocyte nuclear factor 4 gamma
External IDsOMIM: 605966 MGI: 1353604 HomoloGene: 37886 GeneCards: HNF4G
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for HNF4G
Genomic location for HNF4G
Band8q21.13Start75,407,914 bp[1]
End75,566,834 bp[1]
RNA expression pattern
PBB GE HNF4G 207456 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 8: 75.41 – 75.57 MbChr 3: 3.51 – 3.66 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is encoded by the HNF4G gene.[5][6][7]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164749 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017688 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma".
  6. ^ Drewes T, Senkel S, Holewa B, Ryffel GU (March 1996). "Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes". Molecular and Cellular Biology. 16 (3): 925–31. doi:10.1128/mcb.16.3.925. PMC 231074. PMID 8622695.
  7. ^ Wisely GB, Miller AB, Davis RG, Thornquest AD, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP (September 2002). "Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids". Structure. 10 (9): 1225–34. doi:10.1016/S0969-2126(02)00829-8. PMID 12220494.

Further reading[edit]

  • Plengvidhya N, Antonellis A, Wogan LT, Poleev A, Borgschulze M, Warram JH, Ryffel GU, Krolewski AS, Doria A (October 1999). "Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes". Diabetes. 48 (10): 2099–102. doi:10.2337/diabetes.48.10.2099. PMID 10512380.
  • Ozeki T, Takahashi Y, Nakayama K, Funayama M, Nagashima K, Kodama T, Kamataki T (January 2003). "Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers". Pharmacogenetics. 13 (1): 49–53. doi:10.1097/00008571-200301000-00007. PMID 12544512.

External links[edit]