HOXD8

HOXD8
Identifiers
Aliases	HOXD8, HOX4, HOX4E, HOX5.4, homeobox D8
External IDs	OMIM: 142985 MGI: 96209 HomoloGene: 10473 GeneCards: HOXD8
Gene location (Human)
Chr.	Chromosome 2 (human)
End	176,132,695 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	74,538,277 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; Achilles tendon; ; kidney; ; corpus epididymis; ; renal medulla; ; deltoid muscle; ; secondary oocyte; ; caput epididymis; ; smooth muscle tissue; ; sperm;
	Top expressed in
	medullary collecting duct; ; triceps brachii muscle; ; seminal vesicula; ; gastrocnemius muscle; ; kidney; ; epididymis; ; seminiferous tubule; ; dermis; ; spermatid; ; anterior horn of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	anterior/posterior pattern specification; multicellular organism development; anterior/posterior axis specification, embryo; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; skeletal system morphogenesis; transcription, DNA-templated; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3234
	15437
	ENSG00000175879
	ENSMUSG00000027102
	P13378
	P23463
	NM_019558; NM_001199746; NM_001199747
	NM_001290730; NM_001290731; NM_008276
	NP_001186675; NP_001186676; NP_062458
	NP_001277659; NP_001277660; NP_032302
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.^[5]^[6]^[7]

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References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175879 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027102 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

External links

HOXD8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175879 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027102 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

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References

Further reading

External links