HOXD8

HOXD8
Identifiers
Aliases	HOXD8, HOX4, HOX4E, HOX5.4, homeobox D8
External IDs	OMIM: 142985; MGI: 96209; HomoloGene: 10473; GeneCards: HOXD8; OMA:HOXD8 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	176,132,695 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	74,538,277 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; Achilles tendon; ; corpus epididymis; ; renal medulla; ; deltoid muscle; ; secondary oocyte; ; human kidney; ; body of uterus; ; muscle of thigh; ; left ovary;
	Top expressed in
	tail of embryo; ; medullary collecting duct; ; right kidney; ; triceps brachii muscle; ; seminal vesicula; ; gastrocnemius muscle; ; human kidney; ; Gonadal ridge; ; medial head of gastrocnemius muscle; ; efferent ductule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	anterior/posterior pattern specification; multicellular organism development; anterior/posterior axis specification, embryo; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; skeletal system morphogenesis; transcription, DNA-templated; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3234
	15437
	ENSG00000175879
	ENSMUSG00000027102
	P13378
	P23463
	NM_019558; NM_001199746; NM_001199747
	NM_001290730; NM_001290731; NM_008276
	NP_001186675; NP_001186676; NP_062458
	NP_001277659; NP_001277660; NP_032302
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175879 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027102 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

External links

HOXD8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Template:PBB Controls

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175879 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027102 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading

External links