ZNF239

ZNF239
Identifiers
Aliases	ZNF239, HOK-2, MOK2, zinc finger protein 239
External IDs	OMIM: 601069; MGI: 1306812; HomoloGene: 68480; GeneCards: ZNF239; OMA:ZNF239 - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q11.21 Start 43,556,344 bp End 43,574,618 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6 F1|6 55.62 cM Start 117,862,100 bp End 117,873,291 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad endothelial cell testicle ganglionic eminence ventricular zone body of pancreas islet of Langerhans stromal cell of endometrium prefrontal cortex smooth muscle tissue Top expressed in Ileal epithelium cingulate gyrus CA3 field superior frontal gyrus dentate gyrus entorhinal cortex primary visual cortex primary motor cortex perirhinal cortex dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA binding Cellular component nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8187 22685 Ensembl ENSG00000196793 ENSMUSG00000042097 UniProt Q16600 P24399 RefSeq (mRNA) NM_001099282 NM_001099283 NM_001099284 NM_005674 NM_001324347 NM_001324348 NM_001324349 NM_001324350 NM_001324351 NM_001324352 NM_001324353 NM_001001792 NM_008616 NM_001360938 RefSeq (protein) NP_001092752 NP_001092753 NP_001092754 NP_001311276 NP_001311277 NP_001311278 NP_001311279 NP_001311280 NP_001311281 NP_001311282 NP_005665 NP_001001792 NP_032642 NP_001347867 Location (UCSC) Chr 10: 43.56 – 43.57 Mb Chr 6: 117.86 – 117.87 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.

Function

MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures.

Interactions

ZNF239 has been shown to interact with LMNA.

Further reading

• Dreuillet C, Tillit J, Kress M, Ernoult-Lange M (Nov 2002). "In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C". Nucleic Acids Research. 30 (21): 4634–42. doi:10.1093/nar/gkf587. PMC 135794. PMID 12409453.

\* Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• ZNF239+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.