HLF (gene)

HLF
Identifiers
Aliases	HLF, PAR bZIP transcription factor, HLF transcription factor, PAR bZIP family member
External IDs	OMIM: 142385; MGI: 96108; HomoloGene: 31074; GeneCards: HLF; OMA:HLF - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	55,325,187 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	90,281,721 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; orbitofrontal cortex; ; Brodmann area 46; ; superior frontal gyrus; ; prefrontal cortex; ; middle temporal gyrus; ; postcentral gyrus; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; Brodmann area 9;
	Top expressed in
	lateral geniculate nucleus; ; medial dorsal nucleus; ; inferior colliculus; ; medial geniculate nucleus; ; primary motor cortex; ; olfactory tubercle; ; mammillary body; ; pontine nuclei; ; median eminence; ; vestibular membrane of cochlear duct;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; double-stranded DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	multicellular organism development; skeletal muscle cell differentiation; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; rhythmic process; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3131
	217082
	ENSG00000108924
	ENSMUSG00000003949
	Q16534
	Q8BW74
	NM_002126; NM_001330375
	NM_172563
	NP_001317304; NP_002117
NP_766151; NP_001390914; NP_001390915; NP_001390917; NP_001390918;
	NP_001390920; NP_001390922; NP_001390924; NP_001390926
	Wikidata
View/Edit Human	View/Edit Mouse

Hepatic leukemia factor is a protein that in humans is encoded by the HLF gene.^[5]^[6]

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References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000108924 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003949 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Inaba T, Roberts WM, Shapiro LH, Jolly KW, Raimondi SC, Smith SD, Look AT (Aug 1992). "Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia". Science. 257 (5069): 531–4. doi:10.1126/science.1386162. PMID 1386162.
^ "Entrez Gene: HLF hepatic leukemia factor".

External links

HLF+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000108924 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003949 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1386162-5] Inaba T, Roberts WM, Shapiro LH, Jolly KW, Raimondi SC, Smith SD, Look AT (Aug 1992). "Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia". Science. 257 (5069): 531–4. doi:10.1126/science.1386162. PMID 1386162.

[entrez-6] "Entrez Gene: HLF hepatic leukemia factor".

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References

Further reading

External links