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Lysine (K)-specific demethylase 5D
Protein KDM5D PDB 2E6R.png
Rendering based on PDB 2E6R​.
Available structures
PDB Ortholog search: PDBe, RCSB
External IDs OMIM426000 MGI99780 HomoloGene55838 IUPHAR: 2683 GeneCards: KDM5D Gene
RNA expression pattern
PBB GE JARID1D 206700 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8284 20592
Ensembl ENSG00000012817 ENSMUSG00000056673
UniProt Q9BY66 Q62240
RefSeq (mRNA) NM_001146705 NM_011419
RefSeq (protein) NP_001140177 NP_035549
Location (UCSC) Chr Y:
19.7 – 19.74 Mb
Chr Y:
0.9 – 0.96 Mb
PubMed search [1] [2]

Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene.[1][2][3]

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient.[3]


  1. ^ Froggatt P (Feb 1977). "The foundation of the "Inst" medical department and its association with the Belfast Fever Hospital". Ulster Med J 45 (2): 107–45. PMC 2385577. PMID 795123. 
  2. ^ Kent-First MG, Maffitt M, Muallem A, Brisco P, Shultz J, Ekenberg S, Agulnik AI, Agulnik I, Shramm D, Bavister B, Abdul-Mawgood A, VandeBerg J (Nov 1996). "Gene sequence and evolutionary conservation of human SMCY". Nat Genet 14 (2): 128–9. doi:10.1038/ng1096-128. PMID 8841177. 
  3. ^ a b "Entrez Gene: JARID1D jumonji, AT rich interactive domain 1D". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.